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NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice

NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6974709

NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice

About this item

Full title

NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice

Publisher

England: John Wiley & Sons, Inc

Journal title

Aging cell, 2020-01, Vol.19 (1), p.e13050-n/a

Language

English

Formats

Publication information

Publisher

England: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

While NLRP3‐inflammasome has been implicated in cardiovascular diseases, its role in physiological cardiac aging is largely unknown. During aging, many alterations occur in the organism, which are associated with progressive impairment of metabolic pathways related to insulin resistance, autophagy dysfunction, and inflammation. Here, we investigate...

Alternative Titles

Full title

NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6974709

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6974709

Other Identifiers

ISSN

1474-9718

E-ISSN

1474-9726

DOI

10.1111/acel.13050

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