NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice
NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice
About this item
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Author / Creator
Marín‐Aguilar, Fabiola , Lechuga‐Vieco, Ana V. , Alcocer‐Gómez, Elísabet , Castejón‐Vega, Beatriz , Lucas, Javier , Garrido, Carlos , Peralta‐Garcia, Alejandro , Pérez‐Pulido, Antonio J. , Varela‐López, Alfonso , Quiles, José L. , Ryffel, Bernhard , Flores, Ignacio , Bullón, Pedro , Ruiz‐Cabello, Jesús and Cordero, Mario D.
Publisher
England: John Wiley & Sons, Inc
Journal title
Language
English
Formats
Publication information
Publisher
England: John Wiley & Sons, Inc
Subjects
More information
Scope and Contents
Contents
While NLRP3‐inflammasome has been implicated in cardiovascular diseases, its role in physiological cardiac aging is largely unknown. During aging, many alterations occur in the organism, which are associated with progressive impairment of metabolic pathways related to insulin resistance, autophagy dysfunction, and inflammation. Here, we investigate...
Alternative Titles
Full title
NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6974709
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6974709
Other Identifiers
ISSN
1474-9718
E-ISSN
1474-9726
DOI
10.1111/acel.13050
