NK cells clear α-synuclein and the depletion of NK cells exacerbates synuclein pathology in a mouse...
NK cells clear α-synuclein and the depletion of NK cells exacerbates synuclein pathology in a mouse model of α-synucleinopathy
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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The pathological hallmark of synucleinopathies, including Lewy body dementia and Parkinson’s disease (PD), is the presence of Lewy bodies, which are primarily composed of intracellular inclusions of misfolded α-synuclein (α-syn) among other proteins. α-Syn is found in extracellular biological fluids in PD patients and has been implicated in modulat...
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NK cells clear α-synuclein and the depletion of NK cells exacerbates synuclein pathology in a mouse model of α-synucleinopathy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6983411
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6983411
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1909110117
