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Neural stem cell transplantation improves learning and memory by protecting cholinergic neurons and...

Neural stem cell transplantation improves learning and memory by protecting cholinergic neurons and...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7002968

Neural stem cell transplantation improves learning and memory by protecting cholinergic neurons and restoring synaptic impairment in an amyloid precursor protein/presenilin 1 transgenic mouse model of Alzheimer's disease

About this item

Full title

Neural stem cell transplantation improves learning and memory by protecting cholinergic neurons and restoring synaptic impairment in an amyloid precursor protein/presenilin 1 transgenic mouse model of Alzheimer's disease

Publisher

Greece: Spandidos Publications

Journal title

Molecular medicine reports, 2020-03, Vol.21 (3), p.1172-1180

Language

English

Formats

Publication information

Publisher

Greece: Spandidos Publications

More information

Scope and Contents

Contents

Alzheimer's disease (AD) is the most prevalent age‑related neurodegenerative disorder. It is featured by the progressive accumulation of β‑amyloid (Aβ) plaques and neurofibrillary tangles. This can eventually lead to a decrease of cholinergic neurons in the basal forebrain. Stem cell transplantation is an effective treatment for neurodegenerative d...

Alternative Titles

Full title

Neural stem cell transplantation improves learning and memory by protecting cholinergic neurons and restoring synaptic impairment in an amyloid precursor protein/presenilin 1 transgenic mouse model of Alzheimer's disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7002968

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7002968

Other Identifiers

ISSN

1791-2997

E-ISSN

1791-3004

DOI

10.3892/mmr.2020.10918

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