Endothelial sphingosine 1-phosphate receptors promote vascular normalization and antitumor therapy
Endothelial sphingosine 1-phosphate receptors promote vascular normalization and antitumor therapy
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Publisher
United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Sphingosine 1-phosphate receptor-1 (S1PR1) is essential for embryonic vascular development and maturation. In the adult, it is a key regulator of vascular barrier function and inflammatory processes. Its roles in tumor angiogenesis, tumor growth, and metastasis are not well understood. In this paper, we show that S1PR1 is expressed and active in tu...
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Full title
Endothelial sphingosine 1-phosphate receptors promote vascular normalization and antitumor therapy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7022165
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7022165
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1906246117
