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An intrinsic role of IL-33 in Treg cell–mediated tumor immunoevasion

An intrinsic role of IL-33 in Treg cell–mediated tumor immunoevasion

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7030950

An intrinsic role of IL-33 in Treg cell–mediated tumor immunoevasion

About this item

Full title

An intrinsic role of IL-33 in Treg cell–mediated tumor immunoevasion

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2020-01, Vol.21 (1), p.75-85

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Regulatory T (T
reg
) cells accumulate into tumors, hindering the success of cancer immunotherapy. Yet, therapeutic targeting of T
reg
cells shows limited efficacy or leads to autoimmunity. The molecular mechanisms that guide T
reg
cell stability in tumors remain elusive. In the present study, we identify a cell-intrinsic role of...

Alternative Titles

Full title

An intrinsic role of IL-33 in Treg cell–mediated tumor immunoevasion

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7030950

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7030950

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/s41590-019-0555-2

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