Identification of cancer driver genes based on nucleotide context
Identification of cancer driver genes based on nucleotide context
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Cancer genomes contain large numbers of somatic mutations but few of these mutations drive tumor development. Current approaches either identify driver genes on the basis of mutational recurrence or approximate the functional consequences of nonsynonymous mutations by using bioinformatic scores. Passenger mutations are enriched in characteristic nu...
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Full title
Identification of cancer driver genes based on nucleotide context
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7031046
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7031046
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ISSN
1061-4036,1546-1718
E-ISSN
1546-1718
DOI
10.1038/s41588-019-0572-y