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Identification of cancer driver genes based on nucleotide context

Identification of cancer driver genes based on nucleotide context

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7031046

Identification of cancer driver genes based on nucleotide context

About this item

Full title

Identification of cancer driver genes based on nucleotide context

Publisher

New York: Nature Publishing Group US

Journal title

Nature genetics, 2020-02, Vol.52 (2), p.208-218

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Cancer genomes contain large numbers of somatic mutations but few of these mutations drive tumor development. Current approaches either identify driver genes on the basis of mutational recurrence or approximate the functional consequences of nonsynonymous mutations by using bioinformatic scores. Passenger mutations are enriched in characteristic nu...

Alternative Titles

Full title

Identification of cancer driver genes based on nucleotide context

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7031046

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7031046

Other Identifiers

ISSN

1061-4036,1546-1718

E-ISSN

1546-1718

DOI

10.1038/s41588-019-0572-y

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