BRF1 accelerates prostate tumourigenesis and perturbs immune infiltration
BRF1 accelerates prostate tumourigenesis and perturbs immune infiltration
About this item
Full title
Author / Creator
Loveridge, Carolyn J. , Slater, Sarah , Campbell, Kirsteen J. , Nam, Noor A. , Knight, John , Ahmad, Imran , Hedley, Ann , Lilla, Sergio , Repiscak, Peter , Patel, Rachana , Salji, Mark , Fleming, Janis , Mitchell, Louise , Nixon, Colin , Strathdee, Douglas , Neilson, Matthew , Ntala, Chara , Bryson, Sheila , Zanivan, Sara , Edwards, Joanne , Robson, Craig N. , Goodyear, Carl S. , Blyth, Karen and Leung, Hing Y.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
BRF1 is a rate-limiting factor for RNA Polymerase III-mediated transcription and is elevated in numerous cancers. Here, we report that elevated levels of BRF1 associate with poor prognosis in human prostate cancer. In vitro studies in human prostate cancer cell lines demonstrated that transient overexpression of BRF1 increased cell proliferation wh...
Alternative Titles
Full title
BRF1 accelerates prostate tumourigenesis and perturbs immune infiltration
Authors, Artists and Contributors
Author / Creator
Slater, Sarah
Campbell, Kirsteen J.
Nam, Noor A.
Knight, John
Ahmad, Imran
Hedley, Ann
Lilla, Sergio
Repiscak, Peter
Patel, Rachana
Salji, Mark
Fleming, Janis
Mitchell, Louise
Nixon, Colin
Strathdee, Douglas
Neilson, Matthew
Ntala, Chara
Bryson, Sheila
Zanivan, Sara
Edwards, Joanne
Robson, Craig N.
Goodyear, Carl S.
Blyth, Karen
Leung, Hing Y.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7033044
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7033044
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-019-1106-x
