Systematic analysis of the Hippo pathway organization and oncogenic alteration in evolution
Systematic analysis of the Hippo pathway organization and oncogenic alteration in evolution
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
The Hippo pathway is a central regulator of organ size and a key tumor suppressor via coordinating cell proliferation and death. Initially discovered in
Drosophila
, the Hippo pathway has been implicated as an evolutionarily conserved pathway in mammals; however, how this pathway was evolved to be functional from its origin is still largely u...
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Systematic analysis of the Hippo pathway organization and oncogenic alteration in evolution
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7035326
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7035326
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-60120-4
