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HP1 reshapes nucleosome core to promote phase separation of heterochromatin

HP1 reshapes nucleosome core to promote phase separation of heterochromatin

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7039410

HP1 reshapes nucleosome core to promote phase separation of heterochromatin

About this item

Full title

HP1 reshapes nucleosome core to promote phase separation of heterochromatin

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2019-11, Vol.575 (7782), p.390-394

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Heterochromatin affects genome function at many levels. It enables heritable gene repression, maintains chromosome integrity and provides mechanical rigidity to the nucleus
1
,
2
. These diverse functions are proposed to arise in part from compaction of the underlying chromatin
2
. A major type of heterochromatin contains at its c...

Alternative Titles

Full title

HP1 reshapes nucleosome core to promote phase separation of heterochromatin

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7039410

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7039410

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-019-1669-2

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