HP1 reshapes nucleosome core to promote phase separation of heterochromatin
HP1 reshapes nucleosome core to promote phase separation of heterochromatin
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Heterochromatin affects genome function at many levels. It enables heritable gene repression, maintains chromosome integrity and provides mechanical rigidity to the nucleus
1
,
2
. These diverse functions are proposed to arise in part from compaction of the underlying chromatin
2
. A major type of heterochromatin contains at its c...
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Full title
HP1 reshapes nucleosome core to promote phase separation of heterochromatin
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7039410
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7039410
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-019-1669-2