Adjunctive sertraline for HIV-associated cryptococcal meningitis: a randomised, placebo-controlled,...
Adjunctive sertraline for HIV-associated cryptococcal meningitis: a randomised, placebo-controlled, double-blind phase 3 trial
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Author / Creator
ASTRO-CM team , Rhein, Joshua , Huppler Hullsiek, Kathy , Tugume, Lillian , Nuwagira, Edwin , Mpoza, Edward , Evans, Emily E , Kiggundu, Reuben , Pastick, Katelyn A , Ssebambulidde, Kenneth , Akampurira, Andrew , Williams, Darlisha A , Bangdiwala, Ananta S , Abassi, Mahsa , Musubire, Abdu K , Nicol, Melanie R , Muzoora, Conrad , Meya, David B , Boulware, David R , Rhein, Joshua , Huppler Hullsiek, Kathy , Tugume, Lillian , Nuwagira, Edwin , Mpoza, Edward , Evans, Emily E , Kiggundu, Reuben , Pastick, Katelyn A , Ssebambulidde, Kenneth , Akampurira, Andrew , Williams, Darlisha A , Bangdiwala, Ananta S , Abassi, Mahsa , Musubire, Abdu K , Nicol, Melanie R , Muzoora, Conrad , Meya, David B , Boulware, David R , Ndyetukira, Jane Francis , Ahimbisibwe, Cynthia , Kugonza, Florence , Namuju, Carolyne , Sadiq, Alisat , Namudde, Alice , Mwesigye, James , Tadeo, Kiiza K , Kirumira, Paul , Okirwoth, Michael , Luggya, Tonny , Kaboggoza, Julian , Laker, Eva , Atwine, Leo , Muganzi, Davis , Walukaga, Stewart , Jawed, Bilal , Merry, Matthew , Stadelman, Anna , Stephens, Nicole , Flynn, Andrew G , Fujita, Ayako W , Kwizera, Richard , Mukaremera, Liliane , Lofgren, Sarah M , Cresswell, Fiona V , Morawski, Bozena M , Bahr, Nathan C and Nielsen, Kirsten
Publisher
United States: Elsevier Ltd
Journal title
Language
English
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Publication information
Publisher
United States: Elsevier Ltd
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More information
Scope and Contents
Contents
Identifying new antifungals for cryptococcal meningitis is a priority given the inadequacy of current therapy. Sertraline has previously shown in vitro and in vivo activity against cryptococcus. We aimed to assess the efficacy and cost-effectiveness of adjunctive sertraline in adults with HIV-associated cryptococcal meningitis compared with placebo...
Alternative Titles
Full title
Adjunctive sertraline for HIV-associated cryptococcal meningitis: a randomised, placebo-controlled, double-blind phase 3 trial
Authors, Artists and Contributors
Author / Creator
Rhein, Joshua
Huppler Hullsiek, Kathy
Tugume, Lillian
Nuwagira, Edwin
Mpoza, Edward
Evans, Emily E
Kiggundu, Reuben
Pastick, Katelyn A
Ssebambulidde, Kenneth
Akampurira, Andrew
Williams, Darlisha A
Bangdiwala, Ananta S
Abassi, Mahsa
Musubire, Abdu K
Nicol, Melanie R
Muzoora, Conrad
Meya, David B
Boulware, David R
Rhein, Joshua
Huppler Hullsiek, Kathy
Tugume, Lillian
Nuwagira, Edwin
Mpoza, Edward
Evans, Emily E
Kiggundu, Reuben
Pastick, Katelyn A
Ssebambulidde, Kenneth
Akampurira, Andrew
Williams, Darlisha A
Bangdiwala, Ananta S
Abassi, Mahsa
Musubire, Abdu K
Nicol, Melanie R
Muzoora, Conrad
Meya, David B
Boulware, David R
Ndyetukira, Jane Francis
Ahimbisibwe, Cynthia
Kugonza, Florence
Namuju, Carolyne
Sadiq, Alisat
Namudde, Alice
Mwesigye, James
Tadeo, Kiiza K
Kirumira, Paul
Okirwoth, Michael
Luggya, Tonny
Kaboggoza, Julian
Laker, Eva
Atwine, Leo
Muganzi, Davis
Walukaga, Stewart
Jawed, Bilal
Merry, Matthew
Stadelman, Anna
Stephens, Nicole
Flynn, Andrew G
Fujita, Ayako W
Kwizera, Richard
Mukaremera, Liliane
Lofgren, Sarah M
Cresswell, Fiona V
Morawski, Bozena M
Bahr, Nathan C
Nielsen, Kirsten
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7041360
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7041360
Other Identifiers
ISSN
1473-3099
E-ISSN
1474-4457
DOI
10.1016/S1473-3099(19)30127-6
