Long-term expansion, genomic stability and in vivo safety of adult human pancreas organoids
Long-term expansion, genomic stability and in vivo safety of adult human pancreas organoids
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Author / Creator
Georgakopoulos, Nikitas , Prior, Nicole , Angres, Brigitte , Mastrogiovanni, Gianmarco , Cagan, Alex , Harrison, Daisy , Hindley, Christopher J , Arnes-Benito, Robert , Liau, Siong-Seng , Curd, Abbie , Ivory, Natasha , Simons, Benjamin D , Martincorena, Inigo , Wurst, Helmut , Saeb-Parsy, Kourosh and Huch, Meritxell
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Pancreatic organoid systems have recently been described for the in vitro culture of pancreatic ductal cells from mouse and human. Mouse pancreatic organoids exhibit unlimited expansion potential, while previously reported human pancreas organoid (hPO) cultures do not expand efficiently long-term in a chemically defined, serum-free medium. We sough...
Alternative Titles
Full title
Long-term expansion, genomic stability and in vivo safety of adult human pancreas organoids
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7043048
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7043048
Other Identifiers
ISSN
1471-213X
E-ISSN
1471-213X
DOI
10.1186/s12861-020-0209-5
