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Environmental cues regulate epigenetic reprogramming of airway-resident memory CD8+ T cells

Environmental cues regulate epigenetic reprogramming of airway-resident memory CD8+ T cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7044042

Environmental cues regulate epigenetic reprogramming of airway-resident memory CD8+ T cells

About this item

Full title

Environmental cues regulate epigenetic reprogramming of airway-resident memory CD8+ T cells

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2020-03, Vol.21 (3), p.309-320

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Tissue-resident memory T cells (T
RM
cells) are critical for cellular immunity to respiratory pathogens and reside in both the airways and the interstitium. In the present study, we found that the airway environment drove transcriptional and epigenetic changes that specifically regulated the cytolytic functions of airway T
RM
cells and...

Alternative Titles

Full title

Environmental cues regulate epigenetic reprogramming of airway-resident memory CD8+ T cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7044042

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7044042

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/s41590-019-0584-x

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