Environmental cues regulate epigenetic reprogramming of airway-resident memory CD8+ T cells
Environmental cues regulate epigenetic reprogramming of airway-resident memory CD8+ T cells
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Tissue-resident memory T cells (T
RM
cells) are critical for cellular immunity to respiratory pathogens and reside in both the airways and the interstitium. In the present study, we found that the airway environment drove transcriptional and epigenetic changes that specifically regulated the cytolytic functions of airway T
RM
cells and...
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Full title
Environmental cues regulate epigenetic reprogramming of airway-resident memory CD8+ T cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7044042
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7044042
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-019-0584-x