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Tlr9 and Beclin 1 Cross-Talk Regulates Muscle AMPK Activation in Exercise

Tlr9 and Beclin 1 Cross-Talk Regulates Muscle AMPK Activation in Exercise

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7047589

Tlr9 and Beclin 1 Cross-Talk Regulates Muscle AMPK Activation in Exercise

About this item

Full title

Tlr9 and Beclin 1 Cross-Talk Regulates Muscle AMPK Activation in Exercise

Journal title

Nature (London), 2020-02, Vol.578 (7796), p.605-609

Language

English

Formats

More information

Scope and Contents

Contents

The activation of adenosine monophosphate-activated protein kinase (AMPK) in skeletal muscle coordinates systemic metabolic responses to exercise
1
. Autophagy, a lysosomal degradation pathway that maintains cellular homeostasis
2
, is upregulated during exercise, and a core autophagy protein, beclin 1, is required for skeletal muscle A...

Alternative Titles

Full title

Tlr9 and Beclin 1 Cross-Talk Regulates Muscle AMPK Activation in Exercise

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7047589

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7047589

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-020-1992-7

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