Megakaryocytes contain extranuclear histones and may be a source of platelet-associated histones dur...
Megakaryocytes contain extranuclear histones and may be a source of platelet-associated histones during sepsis
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Histones are typically located within the intracellular compartment, and more specifically, within the nucleus. When histones are located within the extracellular compartment, they change roles and become damage-associated molecular patterns (DAMPs), promoting inflammation and coagulation. Patients with sepsis have increased levels of extracellular...
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Full title
Megakaryocytes contain extranuclear histones and may be a source of platelet-associated histones during sepsis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7067782
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7067782
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-61309-3
