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A combat with the YAP/TAZ-TEAD oncoproteins for cancer therapy

A combat with the YAP/TAZ-TEAD oncoproteins for cancer therapy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7069086

A combat with the YAP/TAZ-TEAD oncoproteins for cancer therapy

About this item

Full title

A combat with the YAP/TAZ-TEAD oncoproteins for cancer therapy

Publisher

Australia: Ivyspring International Publisher Pty Ltd

Journal title

Theranostics, 2020-01, Vol.10 (8), p.3622-3635

Language

English

Formats

Publication information

Publisher

Australia: Ivyspring International Publisher Pty Ltd

More information

Scope and Contents

Contents

The transcriptional co-regulators YAP and TAZ pair primarily with the TEAD family of transcription factors to elicit a gene expression signature that plays a prominent role in cancer development, progression and metastasis. YAP and TAZ endow cells with various oncogenic traits such that they sustain proliferation, inhibit apoptosis, maintain stemne...

Alternative Titles

Full title

A combat with the YAP/TAZ-TEAD oncoproteins for cancer therapy

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7069086

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7069086

Other Identifiers

ISSN

1838-7640

E-ISSN

1838-7640

DOI

10.7150/thno.40889

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