Deubiquitylating enzymes and drug discovery: emerging opportunities
Deubiquitylating enzymes and drug discovery: emerging opportunities
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Key Points
The deubiquitylating enzyme (DUB) family contains ~100 proteins that remove the post-translational modification ubiquitin from a variety of substrates.
DUBs have key roles in various areas of cell biology of high relevance to pathologies such as autoimmune disorders, chronic inflammation, oncology and neurodegeneration.
DUBs are...
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Full title
Deubiquitylating enzymes and drug discovery: emerging opportunities
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7097658
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7097658
Other Identifiers
ISSN
1474-1776
E-ISSN
1474-1784
DOI
10.1038/nrd.2017.152
