Use of CAR-Transduced Natural Killer Cells in CD19-Positive Lymphoid Tumors
Use of CAR-Transduced Natural Killer Cells in CD19-Positive Lymphoid Tumors
About this item
Full title
Author / Creator
Liu, Enli , Marin, David , Banerjee, Pinaki , Macapinlac, Homer A , Thompson, Philip , Basar, Rafet , Nassif Kerbauy, Lucila , Overman, Bethany , Thall, Peter , Kaplan, Mecit , Nandivada, Vandana , Kaur, Indresh , Nunez Cortes, Ana , Cao, Kai , Daher, May , Hosing, Chitra , Cohen, Evan N , Kebriaei, Partow , Mehta, Rohtesh , Neelapu, Sattva , Nieto, Yago , Wang, Michael , Wierda, William , Keating, Michael , Champlin, Richard , Shpall, Elizabeth J and Rezvani, Katayoun
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
Using cord blood as an allogeneic lymphocyte source, the investigators in this study infused natural killer cells that had been modified to express an anti-CD19 CAR into 11 patients with CD19-positive lymphoid cancers. Most patients had an antitumor response with very few toxic effects.
Alternative Titles
Full title
Use of CAR-Transduced Natural Killer Cells in CD19-Positive Lymphoid Tumors
Authors, Artists and Contributors
Author / Creator
Marin, David
Banerjee, Pinaki
Macapinlac, Homer A
Thompson, Philip
Basar, Rafet
Nassif Kerbauy, Lucila
Overman, Bethany
Thall, Peter
Kaplan, Mecit
Nandivada, Vandana
Kaur, Indresh
Nunez Cortes, Ana
Cao, Kai
Daher, May
Hosing, Chitra
Cohen, Evan N
Kebriaei, Partow
Mehta, Rohtesh
Neelapu, Sattva
Nieto, Yago
Wang, Michael
Wierda, William
Keating, Michael
Champlin, Richard
Shpall, Elizabeth J
Rezvani, Katayoun
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7101242
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7101242
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1910607