Alternative promoters control UGT2B17-dependent androgen catabolism in prostate cancer and its influ...
Alternative promoters control UGT2B17-dependent androgen catabolism in prostate cancer and its influence on progression
About this item
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Author / Creator
Lévesque, Eric , Labriet, Adrien , Hovington, Hélène , Allain, Éric P. , Melo-Garcia, Luciana , Rouleau, Michèle , Brisson, Hervé , Turcotte, Véronique , Caron, Patrick , Villeneuve, Lyne , Leclercq, Mickaël , Droit, Arnaud , Audet-Walsh, Etienne , Simonyan, David , Fradet, Yves , Lacombe, Louis and Guillemette, Chantal
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Background
Perturbation of the major UGT2B17-dependent androgen catabolism pathway has the potential to affect prostate cancer (PCa) progression. The objective was to evaluate UGT2B17 protein expression in primary tumours in relation to hormone levels, disease characteristics and cancer evolution.
Methods
We conducted an analysis of a high...
Alternative Titles
Full title
Alternative promoters control UGT2B17-dependent androgen catabolism in prostate cancer and its influence on progression
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Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7109100
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7109100
Other Identifiers
ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/s41416-020-0749-2