miR-4711-5p regulates cancer stemness and cell cycle progression via KLF5, MDM2 and TFDP1 in colon c...
miR-4711-5p regulates cancer stemness and cell cycle progression via KLF5, MDM2 and TFDP1 in colon cancer cells
About this item
Full title
Author / Creator
Morimoto, Yoshihiro , Mizushima, Tsunekazu , Wu, Xin , Okuzaki, Daisuke , Yokoyama, Yuhki , Inoue, Akira , Hata, Tsuyoshi , Hirose, Haruka , Qian, Yamin , Wang, Jiaqi , Miyoshi, Norikatsu , Takahashi, Hidekazu , Haraguchi, Naotsugu , Matsuda, Chu , Doki, Yuichiro , Mori, Masaki and Yamamoto, Hirofumi
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Background
It is important to establish cancer stem cell (CSC)-targeted therapies to eradicate cancer. As it is a CSC marker, we focused on
Kruppel-like factor
5 (
KLF5
) in this study.
Methods
We searched for candidate microRNAs (miRNAs) that inhibited
KLF5
expression by in silico analyses and screened them in colon canc...
Alternative Titles
Full title
miR-4711-5p regulates cancer stemness and cell cycle progression via KLF5, MDM2 and TFDP1 in colon cancer cells
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7109136
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7109136
Other Identifiers
ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/s41416-020-0758-1
