Effective drug treatment identified by in vivo screening in a transplantable patient-derived xenogra...
Effective drug treatment identified by in vivo screening in a transplantable patient-derived xenograft model of chronic myelomonocytic leukemia
About this item
Full title
Author / Creator
Kloos, Arnold , Mintzas, Konstantinos , Winckler, Lina , Gabdoulline, Razif , Alwie, Yasmine , Jyotsana, Nidhi , Kattre, Nadine , Schottmann, Renate , Scherr, Michaela , Gupta, Charu , Adams, Felix F. , Schwarzer, Adrian , Heckl, Dirk , Schambach, Axel , Imren, Suzan , Humphries, R. Keith , Ganser, Arnold , Thol, Felicitas and Heuser, Michael
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
To establish novel and effective treatment combinations for chronic myelomonocytic leukemia (CMML) preclinically, we hypothesized that supplementation of CMML cells with the human oncogene
Meningioma 1 (MN1)
promotes expansion and serial transplantability in mice, while maintaining the functional dependencies of these cells on their original...
Alternative Titles
Full title
Effective drug treatment identified by in vivo screening in a transplantable patient-derived xenograft model of chronic myelomonocytic leukemia
Authors, Artists and Contributors
Author / Creator
Mintzas, Konstantinos
Winckler, Lina
Gabdoulline, Razif
Alwie, Yasmine
Jyotsana, Nidhi
Kattre, Nadine
Schottmann, Renate
Scherr, Michaela
Gupta, Charu
Adams, Felix F.
Schwarzer, Adrian
Heckl, Dirk
Schambach, Axel
Imren, Suzan
Humphries, R. Keith
Ganser, Arnold
Thol, Felicitas
Heuser, Michael
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7116758
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7116758
Other Identifiers
ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/s41375-020-0929-3
