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Allele-specific expression changes dynamically during T cell activation in HLA and other autoimmune...

Allele-specific expression changes dynamically during T cell activation in HLA and other autoimmune...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7135372

Allele-specific expression changes dynamically during T cell activation in HLA and other autoimmune loci

About this item

Full title

Allele-specific expression changes dynamically during T cell activation in HLA and other autoimmune loci

Publisher

New York: Nature Publishing Group US

Journal title

Nature genetics, 2020-03, Vol.52 (3), p.247-253

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Genetic studies have revealed that autoimmune susceptibility variants are over-represented in memory CD4
+
T cell regulatory elements
1

3
. Understanding how genetic variation affects gene expression in different T cell physiological states is essential for deciphering genetic mechanisms of autoimmunity
4
,
5
. Here,...

Alternative Titles

Full title

Allele-specific expression changes dynamically during T cell activation in HLA and other autoimmune loci

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7135372

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7135372

Other Identifiers

ISSN

1061-4036

E-ISSN

1546-1718

DOI

10.1038/s41588-020-0579-4

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