Postexposure protection of non-human primates against a lethal Ebola virus challenge with RNA interf...
Postexposure protection of non-human primates against a lethal Ebola virus challenge with RNA interference: a proof-of-concept study
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Publisher
Kidlington: Elsevier Ltd
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Language
English
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Kidlington: Elsevier Ltd
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Summary Background We previously showed that small interfering RNAs (siRNAs) targeting the Zaire Ebola virus (ZEBOV) RNA polymerase L protein formulated in stable nucleic acid-lipid particles (SNALPs) completely protected guineapigs when administered shortly after a lethal ZEBOV challenge. Although rodent models of ZEBOV infection are useful for sc...
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Postexposure protection of non-human primates against a lethal Ebola virus challenge with RNA interference: a proof-of-concept study
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7138079
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7138079
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ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(10)60357-1
