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Novel tau filament fold in corticobasal degeneration

Novel tau filament fold in corticobasal degeneration

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7148158

Novel tau filament fold in corticobasal degeneration

About this item

Full title

Novel tau filament fold in corticobasal degeneration

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2020-04, Vol.580 (7802), p.283-287

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Corticobasal degeneration (CBD) is a neurodegenerative tauopathy—a class of disorders in which the tau protein forms insoluble inclusions in the brain—that is characterized by motor and cognitive disturbances
1

3
. The H1 haplotype of
MAPT
(the tau gene) is present in cases of CBD at a higher frequency than in controls
4
,...

Alternative Titles

Full title

Novel tau filament fold in corticobasal degeneration

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7148158

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7148158

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-020-2043-0

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