Novel tau filament fold in corticobasal degeneration
Novel tau filament fold in corticobasal degeneration
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Corticobasal degeneration (CBD) is a neurodegenerative tauopathy—a class of disorders in which the tau protein forms insoluble inclusions in the brain—that is characterized by motor and cognitive disturbances
1
–
3
. The H1 haplotype of
MAPT
(the tau gene) is present in cases of CBD at a higher frequency than in controls
4
,...
Alternative Titles
Full title
Novel tau filament fold in corticobasal degeneration
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7148158
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7148158
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-020-2043-0