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The antitumorigenic roles of BRCA1–BARD1 in DNA repair and replication

The antitumorigenic roles of BRCA1–BARD1 in DNA repair and replication

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7204409

The antitumorigenic roles of BRCA1–BARD1 in DNA repair and replication

About this item

Full title

The antitumorigenic roles of BRCA1–BARD1 in DNA repair and replication

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Molecular cell biology, 2020-05, Vol.21 (5), p.284-299

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The tumour suppressor breast cancer type 1 susceptibility protein (BRCA1) promotes DNA double-strand break (DSB) repair by homologous recombination and protects DNA replication forks from attrition. BRCA1 partners with BRCA1-associated RING domain protein 1 (BARD1) and other tumour suppressor proteins to mediate the initial nucleolytic resection of...

Alternative Titles

Full title

The antitumorigenic roles of BRCA1–BARD1 in DNA repair and replication

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7204409

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7204409

Other Identifiers

ISSN

1471-0072

E-ISSN

1471-0080

DOI

10.1038/s41580-020-0218-z

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