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Human multi-organ chip co-culture of bronchial lung culture and liver spheroids for substance exposu...

Human multi-organ chip co-culture of bronchial lung culture and liver spheroids for substance exposu...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7217973

Human multi-organ chip co-culture of bronchial lung culture and liver spheroids for substance exposure studies

About this item

Full title

Human multi-organ chip co-culture of bronchial lung culture and liver spheroids for substance exposure studies

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2020-05, Vol.10 (1), p.7865, Article 7865

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Extrapolation of cell culture-based test results to
in vivo
effects is limited, as cell cultures fail to emulate organ complexity and multi-tissue crosstalk. Biology-inspired microphysiological systems provide preclinical insights into absorption, distribution, metabolism, excretion, and toxicity of substances
in vitro
by using human th...

Alternative Titles

Full title

Human multi-organ chip co-culture of bronchial lung culture and liver spheroids for substance exposure studies

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7217973

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7217973

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-020-64219-6

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