Gene rearrangements of MLL and RUNX1 sporadically occur in normal CD34+ cells under cytokine stimula...
Gene rearrangements of MLL and RUNX1 sporadically occur in normal CD34+ cells under cytokine stimulation
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Publisher
England: John Wiley & Sons, Inc
Journal title
Language
English
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Publisher
England: John Wiley & Sons, Inc
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Scope and Contents
Contents
Gene rearrangements of MLL/KMT2A or RUNX1 are the major cause of therapy‐related leukemia. Moreover, MLL rearrangements are the major cause of infant leukemia, and RUNX1 rearrangements are frequently detected in cord blood. These genes are sensitive to topoisomerase II inhibitors, and various genes have been identified as potential fusion partners....
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Full title
Gene rearrangements of MLL and RUNX1 sporadically occur in normal CD34+ cells under cytokine stimulation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7226195
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7226195
Other Identifiers
ISSN
1347-9032
E-ISSN
1349-7006
DOI
10.1111/cas.14392
