Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephal...
Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype
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Author / Creator
Hou, Baohua , Zhang, Yahui , Liang, Peiyu , He, Yuan , Peng, Biwen , Liu, Wanhong , Han, Song , Yin, Jun and He, Xiaohua
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
ABSTRACT
Multiple sclerosis (MS) is a chronic disease that is characterized by demyelination and axonal damage in the central nervous system. Cognitive deficits are recognized as one of the features of MS, and these deficits affect the patients’ quality of life. Increasing evidence from experimental autoimmune encephalomyelitis (EAE), the animal...
Alternative Titles
Full title
Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7229224
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7229224
Other Identifiers
ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-020-2565-2
