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Spatial reconstruction of immune niches by combining photoactivatable reporters and scRNA-seq

Spatial reconstruction of immune niches by combining photoactivatable reporters and scRNA-seq

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7234837

Spatial reconstruction of immune niches by combining photoactivatable reporters and scRNA-seq

About this item

Full title

Spatial reconstruction of immune niches by combining photoactivatable reporters and scRNA-seq

Publisher

United States: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2017-12, Vol.358 (6370), p.1622-1627

Language

English

Formats

Publication information

Publisher

United States: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Cellular functions are strongly dependent on surrounding cells and environmental factors. Current technologies are limited in their ability to characterize the spatial location and gene programs of cells in poorly structured and dynamic niches. We developed a method, NICHE-seq, that combines photoactivatable fluorescent reporters, two-photon micros...

Alternative Titles

Full title

Spatial reconstruction of immune niches by combining photoactivatable reporters and scRNA-seq

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7234837

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7234837

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.aao4277

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