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An immune-cell signature of bacterial sepsis

An immune-cell signature of bacterial sepsis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7235950

An immune-cell signature of bacterial sepsis

About this item

Full title

An immune-cell signature of bacterial sepsis

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2020-03, Vol.26 (3), p.333-340

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Dysregulation of the immune response to bacterial infection can lead to sepsis, a condition with high mortality. Multiple whole-blood gene-expression studies have defined sepsis-associated molecular signatures, but have not resolved changes in transcriptional states of specific cell types. Here, we used single-cell RNA-sequencing to profile the blo...

Alternative Titles

Full title

An immune-cell signature of bacterial sepsis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7235950

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7235950

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/s41591-020-0752-4

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