RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response
RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response
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Author / Creator
RePORT Brazil Team , SATVI Clinical and Laboratory Team , GC6-74 Consortium , Adolescent Cohort Study team , Peruvian Household Contacts Cohort Team , AE-TBC Consortium , CAPRISA IMPRESS team , ScreenTB Consortium , The CAPRISA IMPRESS team , The Adolescent Cohort Study team , The GC6-74 Consortium , The AE-TBC Consortium , The RePORT Brazil Team , The ScreenTB Consortium , The SATVI Clinical and Laboratory Team , Penn-Nicholson, Adam , Mbandi, Stanley Kimbung , Thompson, Ethan , Mendelsohn, Simon C. , Suliman, Sara , Chegou, Novel N. , Malherbe, Stephanus T. , Darboe, Fatoumatta , Erasmus, Mzwandile , Hanekom, Willem A. , Bilek, Nicole , Fisher, Michelle , Kaufmann, Stefan H. E. , Winter, Jill , Murphy, Melissa , Wood, Robin , Morrow, Carl , Van Rhijn, Ildiko , Moody, Branch , Murray, Megan , Andrade, Bruno B. , Sterling, Timothy R. , Sutherland, Jayne , Naidoo, Kogieleum , Padayatchi, Nesri , Walzl, Gerhard , Hatherill, Mark , Zak, Daniel and Scriba, Thomas J.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Improved tuberculosis diagnostics and tools for monitoring treatment response are urgently needed. We developed a robust and simple, PCR-based host-blood transcriptomic signature, RISK6, for multiple applications: identifying individuals at risk of incident disease, as a screening test for subclinical or clinical tuberculosis, and for monitoring tu...
Alternative Titles
Full title
RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response
Authors, Artists and Contributors
Author / Creator
SATVI Clinical and Laboratory Team
GC6-74 Consortium
Adolescent Cohort Study team
Peruvian Household Contacts Cohort Team
AE-TBC Consortium
CAPRISA IMPRESS team
ScreenTB Consortium
The CAPRISA IMPRESS team
The Adolescent Cohort Study team
The GC6-74 Consortium
The AE-TBC Consortium
The RePORT Brazil Team
The ScreenTB Consortium
The SATVI Clinical and Laboratory Team
Penn-Nicholson, Adam
Mbandi, Stanley Kimbung
Thompson, Ethan
Mendelsohn, Simon C.
Suliman, Sara
Chegou, Novel N.
Malherbe, Stephanus T.
Darboe, Fatoumatta
Erasmus, Mzwandile
Hanekom, Willem A.
Bilek, Nicole
Fisher, Michelle
Kaufmann, Stefan H. E.
Winter, Jill
Murphy, Melissa
Wood, Robin
Morrow, Carl
Van Rhijn, Ildiko
Moody, Branch
Murray, Megan
Andrade, Bruno B.
Sterling, Timothy R.
Sutherland, Jayne
Naidoo, Kogieleum
Padayatchi, Nesri
Walzl, Gerhard
Hatherill, Mark
Zak, Daniel
Scriba, Thomas J.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7248089
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7248089
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-65043-8