Centrosome reduction in newly-generated tetraploid cancer cells obtained by separase depletion
Centrosome reduction in newly-generated tetraploid cancer cells obtained by separase depletion
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Tetraploidy, a common feature in cancer, results in the presence of extra centrosomes, which has been associated with chromosome instability (CIN) and aneuploidy. Deregulation in the number of centrosomes triggers tumorigenesis. However, how supernumerary centrosomes evolve during the emergence of tetraploid cells remains yet to be elucidated. Here...
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Centrosome reduction in newly-generated tetraploid cancer cells obtained by separase depletion
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7272426
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7272426
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-65975-1