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Centrosome reduction in newly-generated tetraploid cancer cells obtained by separase depletion

Centrosome reduction in newly-generated tetraploid cancer cells obtained by separase depletion

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7272426

Centrosome reduction in newly-generated tetraploid cancer cells obtained by separase depletion

About this item

Full title

Centrosome reduction in newly-generated tetraploid cancer cells obtained by separase depletion

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2020-06, Vol.10 (1), p.9152-9152, Article 9152

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Tetraploidy, a common feature in cancer, results in the presence of extra centrosomes, which has been associated with chromosome instability (CIN) and aneuploidy. Deregulation in the number of centrosomes triggers tumorigenesis. However, how supernumerary centrosomes evolve during the emergence of tetraploid cells remains yet to be elucidated. Here...

Alternative Titles

Full title

Centrosome reduction in newly-generated tetraploid cancer cells obtained by separase depletion

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7272426

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7272426

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-020-65975-1

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