Microbial bile acid metabolites modulate gut RORγ+ regulatory T cell homeostasis
Microbial bile acid metabolites modulate gut RORγ+ regulatory T cell homeostasis
About this item
Full title
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The metabolic pathways encoded by the human gut microbiome constantly interact with host gene products through numerous bioactive molecules
1
. Primary bile acids (BAs) are synthesized within hepatocytes and released into the duodenum to facilitate absorption of lipids or fat-soluble vitamins
2
. Some BAs (approximately 5%) escape into...
Alternative Titles
Full title
Microbial bile acid metabolites modulate gut RORγ+ regulatory T cell homeostasis
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7274525
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7274525
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-019-1865-0
