Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation
Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The biological function of Z-DNA and Z-RNA, nucleic acid structures with a left-handed double helix, is poorly understood
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–
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. Z-DNA-binding protein 1 (ZBP1; also known as DAI or DLM-1) is a nucleic acid sensor that contains two Zα domains that bind Z-DNA
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,
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and Z-RNA
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–
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. ZBP1 mediates host defence agai...
Alternative Titles
Full title
Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7279955
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7279955
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-020-2129-8
