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MAPT mutations, tauopathy, and mechanisms of neurodegeneration

MAPT mutations, tauopathy, and mechanisms of neurodegeneration

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7289372

MAPT mutations, tauopathy, and mechanisms of neurodegeneration

About this item

Full title

MAPT mutations, tauopathy, and mechanisms of neurodegeneration

Publisher

New York: Elsevier Inc

Journal title

Laboratory investigation, 2019-07, Vol.99 (7), p.912-928

Language

English

Formats

Publication information

Publisher

New York: Elsevier Inc

More information

Scope and Contents

Contents

In multiple neurodegenerative diseases, including Alzheimer's disease (AD), a prominent pathological feature is the aberrant aggregation and inclusion formation of the microtubule-associated protein tau. Because of the pathological association, these disorders are often referred to as tauopathies. Mutations in the MAPT gene that encodes tau can cau...

Alternative Titles

Full title

MAPT mutations, tauopathy, and mechanisms of neurodegeneration

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7289372

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7289372

Other Identifiers

ISSN

0023-6837,1530-0307

E-ISSN

1530-0307

DOI

10.1038/s41374-019-0197-x

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