Low-frequency ultrasound-mediated cytokine transfection enhances T cell recruitment at local and dis...
Low-frequency ultrasound-mediated cytokine transfection enhances T cell recruitment at local and distant tumor sites
About this item
Full title
Author / Creator
Ilovitsh, Tali , Feng, Yi , Foiret, Josquin , Kheirolomoom, Azadeh , Zhang, Hua , Ingham, Elizabeth S. , Ilovitsh, Asaf , Tumbale, Spencer K. , Fite, Brett Z. , Wu, Bo , Raie, Marina N. , Zhang, Nisi , Kare, Aris J. , Chavez, Michael , Qi, Lei S. , Pelled, Gadi , Gazit, Dan , Vermesh, Ophir , Steinberg, Idan , Gambhir, Sanjiv S. and Ferrara, Katherine W.
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Robust cytotoxic T cell infiltration has proven to be difficult to achieve in solid tumors. We set out to develop a flexible protocol to efficiently transfect tumor and stromal cells to produce immune-activating cytokines, and thus enhance T cell infiltration while debulking tumor mass. By combining ultrasound with tumortargeted microbubbles, membr...
Alternative Titles
Full title
Low-frequency ultrasound-mediated cytokine transfection enhances T cell recruitment at local and distant tumor sites
Authors, Artists and Contributors
Author / Creator
Feng, Yi
Foiret, Josquin
Kheirolomoom, Azadeh
Zhang, Hua
Ingham, Elizabeth S.
Ilovitsh, Asaf
Tumbale, Spencer K.
Fite, Brett Z.
Wu, Bo
Raie, Marina N.
Zhang, Nisi
Kare, Aris J.
Chavez, Michael
Qi, Lei S.
Pelled, Gadi
Gazit, Dan
Vermesh, Ophir
Steinberg, Idan
Gambhir, Sanjiv S.
Ferrara, Katherine W.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7293655
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7293655
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1914906117