Massively parallel single-cell chromatin landscapes of human immune cell development and intratumora...
Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion
About this item
Full title
Author / Creator
Satpathy, Ansuman T. , Granja, Jeffrey M. , Yost, Kathryn E. , Qi, Yanyan , Meschi, Francesca , McDermott, Geoffrey P. , Olsen, Brett N. , Mumbach, Maxwell R. , Pierce, Sarah E. , Corces, M. Ryan , Shah, Preyas , Bell, Jason C. , Jhutty, Darisha , Nemec, Corey M. , Wang, Jean , Wang, Li , Yin, Yifeng , Giresi, Paul G. , Chang, Anne Lynn S. , Zheng, Grace X. Y. , Greenleaf, William J. and Chang, Howard Y.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
Understanding complex tissues requires single-cell deconstruction of gene regulation with precision and scale. Here, we assess the performance of a massively parallel droplet-based method for mapping transposase-accessible chromatin in single cells using sequencing (scATAC-seq). We apply scATAC-seq to obtain chromatin profiles of more than 200,000...
Alternative Titles
Full title
Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion
Authors, Artists and Contributors
Author / Creator
Granja, Jeffrey M.
Yost, Kathryn E.
Qi, Yanyan
Meschi, Francesca
McDermott, Geoffrey P.
Olsen, Brett N.
Mumbach, Maxwell R.
Pierce, Sarah E.
Corces, M. Ryan
Shah, Preyas
Bell, Jason C.
Jhutty, Darisha
Nemec, Corey M.
Wang, Jean
Wang, Li
Yin, Yifeng
Giresi, Paul G.
Chang, Anne Lynn S.
Zheng, Grace X. Y.
Greenleaf, William J.
Chang, Howard Y.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7299161
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7299161
Other Identifiers
ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/s41587-019-0206-z
