Sanguisorba officinalis L. derived from herbal medicine prevents intestinal inflammation by inducing...
Sanguisorba officinalis L. derived from herbal medicine prevents intestinal inflammation by inducing autophagy in macrophages
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Author / Creator
Yasueda, Asuka , Kayama, Hisako , Murohashi, Michiko , Nishimura, Junichi , Wakame, Koji , Komatsu, Ken-ichi , Ogino, Takayuki , Miyoshi, Norikatsu , Takahashi, Hidekazu , Uemura, Mamoru , Matsuda, Chu , Kitagawa, Toru , Takeda, Kiyoshi , Ito, Toshinori , Doki, Yuichiro , Eguchi, Hidetoshi , Shimizu, Shigeomi and Mizushima, Tsunekazu
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Disturbed activation of autophagy is implicated in the pathogenesis of inflammatory bowel disease. Accordingly, several autophagy-related genes have been identified as Crohn’s disease susceptibility genes. We screened the autophagy activators from a library including 3,922 natural extracts using a high-throughput assay system. The extracts identifi...
Alternative Titles
Full title
Sanguisorba officinalis L. derived from herbal medicine prevents intestinal inflammation by inducing autophagy in macrophages
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7305163
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7305163
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-65306-4
