Active and repressed biosynthetic gene clusters have spatially distinct chromosome states
Active and repressed biosynthetic gene clusters have spatially distinct chromosome states
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Washington: National Academy of Sciences
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Language
English
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Washington: National Academy of Sciences
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While colocalization within a bacterial operon enables coexpression of the constituent genes, the mechanistic logic of clustering of nonhomologous monocistronic genes in eukaryotes is not immediately obvious. Biosynthetic gene clusters that encode pathways for specialized metabolites are an exception to the classical eukaryote rule of random gene l...
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Active and repressed biosynthetic gene clusters have spatially distinct chromosome states
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7306824
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7306824
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1920474117