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Sensory nerves regulate mesenchymal stromal cell lineage commitment by tuning sympathetic tones

Sensory nerves regulate mesenchymal stromal cell lineage commitment by tuning sympathetic tones

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7324175

Sensory nerves regulate mesenchymal stromal cell lineage commitment by tuning sympathetic tones

About this item

Full title

Sensory nerves regulate mesenchymal stromal cell lineage commitment by tuning sympathetic tones

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2020-07, Vol.130 (7), p.3483-3498

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

The sensory nerve was recently identified as being involved in regulation of bone mass accrual. We previously discovered that prostaglandin E2 (PGE2) secreted by osteoblasts could activate sensory nerve EP4 receptor to promote bone formation by inhibiting sympathetic activity. However, the fundamental units of bone formation are active osteoblasts,...

Alternative Titles

Full title

Sensory nerves regulate mesenchymal stromal cell lineage commitment by tuning sympathetic tones

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7324175

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7324175

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI131554

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