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TIM3 comes of age as an inhibitory receptor

TIM3 comes of age as an inhibitory receptor

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7327798

TIM3 comes of age as an inhibitory receptor

About this item

Full title

TIM3 comes of age as an inhibitory receptor

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Immunology, 2020-03, Vol.20 (3), p.173-185

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

T cell immunoglobulin and mucin domain-containing protein 3 (TIM3), a member of the TIM family, was originally identified as a receptor expressed on interferon-γ-producing CD4
+
and CD8
+
T cells. Initial data indicated that TIM3 functioned as a ‘co-inhibitory’ or ‘checkpoint’ receptor, but due to the lack of a definable inhibitory sign...

Alternative Titles

Full title

TIM3 comes of age as an inhibitory receptor

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7327798

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7327798

Other Identifiers

ISSN

1474-1733

E-ISSN

1474-1741

DOI

10.1038/s41577-019-0224-6

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