ULK1 and ULK2 are less redundant than previously thought: computational analysis uncovers distinct r...
ULK1 and ULK2 are less redundant than previously thought: computational analysis uncovers distinct regulation and functions of these autophagy induction proteins
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Macroautophagy, the degradation of cytoplasmic content by lysosomal fusion, is an evolutionary conserved process promoting homeostasis and intracellular defence. Macroautophagy is initiated primarily by a complex containing ULK1 or ULK2 (two paralogs of the yeast Atg1 protein). To understand the differences between ULK1 and ULK2, we compared the hu...
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ULK1 and ULK2 are less redundant than previously thought: computational analysis uncovers distinct regulation and functions of these autophagy induction proteins
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7331686
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7331686
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-67780-2
