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Cryo-EM structures of inactive and active GABAB receptor

Cryo-EM structures of inactive and active GABAB receptor

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7343782

Cryo-EM structures of inactive and active GABAB receptor

About this item

Full title

Cryo-EM structures of inactive and active GABAB receptor

Publisher

Singapore: Springer Singapore

Journal title

Cell research, 2020-07, Vol.30 (7), p.564-573

Language

English

Formats

Publication information

Publisher

Singapore: Springer Singapore

More information

Scope and Contents

Contents

Metabotropic GABA
B
G protein-coupled receptor functions as a mandatory heterodimer of GB1 and GB2 subunits and mediates inhibitory neurotransmission in the central nervous system. Each subunit is composed of the extracellular Venus flytrap (VFT) domain and transmembrane (TM) domain. Here we present cryo-EM structures of full-length human het...

Alternative Titles

Full title

Cryo-EM structures of inactive and active GABAB receptor

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7343782

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7343782

Other Identifiers

ISSN

1001-0602

E-ISSN

1748-7838

DOI

10.1038/s41422-020-0350-5

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