Rationally Designed Antibodies as Research Tools to Study the Structure-Toxicity Relationship of Amy...
Rationally Designed Antibodies as Research Tools to Study the Structure-Toxicity Relationship of Amyloid-β Oligomers
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Author / Creator
Limbocker, Ryan , Mannini, Benedetta , Cataldi, Rodrigo , Chhangur, Shianne , Wright, Aidan K , Kreiser, Ryan P , Albright, J Alex , Chia, Sean , Habchi, Johnny , Sormanni, Pietro , Kumita, Janet R , Ruggeri, Francesco S , Dobson, Christopher M , Chiti, Fabrizio , Aprile, Francesco A and Vendruscolo, Michele
Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
Alzheimer's disease is associated with the aggregation of the amyloid-β peptide (Aβ), resulting in the deposition of amyloid plaques in brain tissue. Recent scrutiny of the mechanisms by which Aβ aggregates induce neuronal dysfunction has highlighted the importance of the Aβ oligomers of this protein fragment. Because of the transient and heterogen...
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Full title
Rationally Designed Antibodies as Research Tools to Study the Structure-Toxicity Relationship of Amyloid-β Oligomers
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7352524
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7352524
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms21124542
