Transcription Factor Nrf2 as a Potential Therapeutic Target for Prevention of Cytokine Storm in COVI...
Transcription Factor Nrf2 as a Potential Therapeutic Target for Prevention of Cytokine Storm in COVID-19 Patients
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Publisher
Moscow: Pleiades Publishing
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Language
English
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Publisher
Moscow: Pleiades Publishing
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Scope and Contents
Contents
Nrf2 is a key transcription factor responsible for antioxidant defense in many tissues and cells, including alveolar epithelium, endothelium, and macrophages. Furthermore, Nrf2 functions as a transcriptional repressor that inhibits expression of the inflammatory cytokines in macrophages. Critically ill patients with COVID-19 infection often present...
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Full title
Transcription Factor Nrf2 as a Potential Therapeutic Target for Prevention of Cytokine Storm in COVID-19 Patients
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7356136
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7356136
Other Identifiers
ISSN
0006-2979
E-ISSN
1608-3040
DOI
10.1134/S0006297920070111
