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NFI transcription factors provide chromatin access to maintain stem cell identity while preventing u...

NFI transcription factors provide chromatin access to maintain stem cell identity while preventing u...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7367149

NFI transcription factors provide chromatin access to maintain stem cell identity while preventing unintended lineage fate choices

About this item

Full title

NFI transcription factors provide chromatin access to maintain stem cell identity while preventing unintended lineage fate choices

Publisher

London: Nature Publishing Group UK

Journal title

Nature cell biology, 2020-06, Vol.22 (6), p.640-650

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Tissue homeostasis and regeneration rely on resident stem cells (SCs), whose behaviour is regulated through niche-dependent crosstalk. The mechanisms underlying SC identity are still unfolding. Here, using spatiotemporal gene ablation in murine hair follicles, we uncover a critical role for the transcription factors (TFs) nuclear factor IB (NFIB) a...

Alternative Titles

Full title

NFI transcription factors provide chromatin access to maintain stem cell identity while preventing unintended lineage fate choices

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7367149

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7367149

Other Identifiers

ISSN

1465-7392

E-ISSN

1476-4679

DOI

10.1038/s41556-020-0513-0

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