A rectal cancer organoid platform to study individual responses to chemoradiation
A rectal cancer organoid platform to study individual responses to chemoradiation
About this item
Full title
Author / Creator
Ganesh, Karuna , Wu, Chao , O’Rourke, Kevin P. , Szeglin, Bryan C. , Zheng, Youyun , Sauvé, Charles-Etienne Gabriel , Adileh, Mohammad , Wasserman, Isaac , Marco, Michael R. , Kim, Amanda S. , Shady, Maha , Sanchez-Vega, Francisco , Karthaus, Wouter R. , Won, Helen H. , Choi, Seo-Hyun , Pelossof, Raphael , Barlas, Afsar , Ntiamoah, Peter , Pappou, Emmanouil , Elghouayel, Arthur , Strong, James S. , Chen, Chin-Tung , Harris, Jennifer W. , Weiser, Martin R. , Nash, Garrett M. , Guillem, Jose G. , Wei, Iris H. , Kolesnick, Richard N. , Veeraraghavan, Harini , Ortiz, Eduardo J. , Petkovska, Iva , Cercek, Andrea , Manova-Todorova, Katia O. , Saltz, Leonard B. , Lavery, Jessica A. , DeMatteo, Ronald P. , Massagué, Joan , Paty, Philip B. , Yaeger, Rona , Chen, Xi , Patil, Sujata , Clevers, Hans , Berger, Michael F. , Lowe, Scott W. , Shia, Jinru , Romesser, Paul B. , Dow, Lukas E. , Garcia-Aguilar, Julio , Sawyers, Charles L. and Smith, J. Joshua
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Rectal cancer (RC) is a challenging disease to treat that requires chemotherapy, radiation and surgery to optimize outcomes for individual patients. No accurate model of RC exists to answer fundamental research questions relevant to patients. We established a biorepository of 65 patient-derived RC organoid cultures (tumoroids) from patients with pr...
Alternative Titles
Full title
A rectal cancer organoid platform to study individual responses to chemoradiation
Authors, Artists and Contributors
Author / Creator
Wu, Chao
O’Rourke, Kevin P.
Szeglin, Bryan C.
Zheng, Youyun
Sauvé, Charles-Etienne Gabriel
Adileh, Mohammad
Wasserman, Isaac
Marco, Michael R.
Kim, Amanda S.
Shady, Maha
Sanchez-Vega, Francisco
Karthaus, Wouter R.
Won, Helen H.
Choi, Seo-Hyun
Pelossof, Raphael
Barlas, Afsar
Ntiamoah, Peter
Pappou, Emmanouil
Elghouayel, Arthur
Strong, James S.
Chen, Chin-Tung
Harris, Jennifer W.
Weiser, Martin R.
Nash, Garrett M.
Guillem, Jose G.
Wei, Iris H.
Kolesnick, Richard N.
Veeraraghavan, Harini
Ortiz, Eduardo J.
Petkovska, Iva
Cercek, Andrea
Manova-Todorova, Katia O.
Saltz, Leonard B.
Lavery, Jessica A.
DeMatteo, Ronald P.
Massagué, Joan
Paty, Philip B.
Yaeger, Rona
Chen, Xi
Patil, Sujata
Clevers, Hans
Berger, Michael F.
Lowe, Scott W.
Shia, Jinru
Romesser, Paul B.
Dow, Lukas E.
Garcia-Aguilar, Julio
Sawyers, Charles L.
Smith, J. Joshua
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7385919
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7385919
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-019-0584-2
