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Yaeger, Rona Denit
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: WIE-ZYW, 2022, p.12572-12572
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Yaeger, Rona Denit
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: WIL-ZYW, 2021, p.12540-12540
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ArticlesPeer ReviewedFull Text
Chromothripsis drives the evolution of gene amplification in cancer
Author / Creator:Shoshani, Ofer ; Brunner, Simon F. ; Yaeger, Rona ; Ly, Peter ; Nechemia-Arbely, Yael ; Kim, Dong Hyun ; Fang, Rongxin ; Castillon, Guillaume A. ; Yu, Miao ; Li, Julia S. Z. ; Sun, Ying ; Ellisman, Mark H. ; Ren, Bing ; Campbell, Peter J. ; Cleveland, Don W.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2021-03, Vol.591 (7848), p.137-141
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Encorafenib, Binimetinib, and Cetuximab in BRAF V600E–Mutated Colorectal Cancer
Author / Creator:Kopetz, Scott ; Grothey, Axel ; Yaeger, Rona ; Van Cutsem, Eric ; Desai, Jayesh ; Yoshino, Takayuki ; Wasan, Harpreet ; Ciardiello, Fortunato ; Loupakis, Fotios ; Hong, Yong Sang ; Steeghs, Neeltje ; Guren, Tormod K ; Arkenau, Hendrik-Tobias ; Garcia-Alfonso, Pilar ; Pfeiffer, Per ; Orlov, Sergey ; Lonardi, Sara ; Elez, Elena ; Kim, Tae-Won ; Schellens, Jan H.M ; Guo, Christina ; Krishnan, Asha ; Dekervel, Jeroen ; Morris, Van ; Calvo Ferrandiz, Aitana ; Tarpgaard, L.S ; Braun, Michael ; Gollerkeri, Ashwin ; Keir, Christopher ; Maharry, Kati ; Pickard, Michael ; Christy-Bittel, Janna ; Anderson, Lisa ; Sandor, Victor ; Tabernero, Josep
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2019-10, Vol.381 (17), p.1632-1643
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Heat Shock Factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer
Author / Creator:Levi-Galibov, Oshrat ; Lavon, Hagar ; Wassermann-Dozorets, Rina ; Pevsner-Fischer, Meirav ; Mayer, Shimrit ; Wershof, Esther ; Stein, Yaniv ; Brown, Lauren E. ; Zhang, Wenhan ; Friedman, Gil ; Nevo, Reinat ; Golani, Ofra ; Katz, Lior H. ; Yaeger, Rona ; Laish, Ido ; Porco, John A. ; Sahai, Erik ; Shouval, Dror S. ; Kelsen, David ; Scherz-Shouval, Ruth
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-12, Vol.11 (1), p.6245-6245, Article 6245
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Different hotspot p53 mutants exert distinct phenotypes and predict outcome of colorectal cancer patients
Author / Creator:Hassin, Ori ; Nataraj, Nishanth Belugali ; Shreberk-Shaked, Michal ; Aylon, Yael ; Yaeger, Rona ; Fontemaggi, Giulia ; Mukherjee, Saptaparna ; Maddalena, Martino ; Avioz, Adi ; Iancu, Ortal ; Mallel, Giuseppe ; Gershoni, Anat ; Grosheva, Inna ; Feldmesser, Ester ; Ben-Dor, Shifra ; Golani, Ofra ; Hendel, Ayal ; Blandino, Giovanni ; Kelsen, David ; Yarden, Yosef ; Oren, Moshe
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-05, Vol.13 (1), p.2800-2800, Article 2800
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ArticlesPeer ReviewedFull Text
S1014 Immune Checkpoint Inhibitors for Colorectal Cancer in Patients With Inflammatory Bowel Disease
Author / Creator:Faleck, David M. ; Sharma, Konika ; Yaeger, Rona ; Kelsen, David
Publisher:Philadelphia, PA: Wolters Kluwer
Journal title:The American journal of gastroenterology, 2022-10, Vol.117 (10S), p.e734-e735
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ArticlesPeer ReviewedFull Text
Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer
Author / Creator:Misale, Sandra ; Yaeger, Rona ; Hobor, Sebastijan ; Scala, Elisa ; Janakiraman, Manickam ; Liska, David ; Valtorta, Emanuele ; Schiavo, Roberta ; Buscarino, Michela ; Siravegna, Giulia ; Bencardino, Katia ; Cercek, Andrea ; Chen, Chin-Tung ; Veronese, Silvio ; Zanon, Carlo ; Sartore-Bianchi, Andrea ; Gambacorta, Marcello ; Gallicchio, Margherita ; Vakiani, Efsevia ; Boscaro, Valentina ; Medico, Enzo ; Weiser, Martin ; Siena, Salvatore ; Di Nicolantonio, Federica ; Solit, David ; Bardelli, Alberto
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2012-06, Vol.486 (7404), p.532-536
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ctDNA applications and integration in colorectal cancer: an NCI Colon and Rectal–Anal Task Forces whitepaper
Author / Creator:Dasari, Arvind ; Morris, Van K. ; Allegra, Carmen J. ; Atreya, Chloe ; Benson, Al B. ; Boland, Patrick ; Chung, Ki ; Copur, Mehmet S. ; Corcoran, Ryan B. ; Deming, Dustin A. ; Dwyer, Andrea ; Diehn, Maximilian ; Eng, Cathy ; George, Thomas J. ; Gollub, Marc J. ; Goodwin, Rachel A. ; Hamilton, Stanley R. ; Hechtman, Jaclyn F. ; Hochster, Howard ; Hong, Theodore S. ; Innocenti, Federico ; Iqbal, Atif ; Jacobs, Samuel A. ; Kennecke, Hagen F. ; Lee, James J. ; Lieu, Christopher H. ; Lenz, Heinz-Josef ; Lindwasser, O. Wolf ; Montagut, Clara ; Odisio, Bruno ; Ou, Fang-Shu ; Porter, Laura ; Raghav, Kanwal ; Schrag, Deborah ; Scott, Aaron J. ; Shi, Qian ; Strickler, John H. ; Venook, Alan ; Yaeger, Rona ; Yothers, Greg ; You, Y. Nancy ; Zell, Jason A. ; Kopetz, Scott
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Clinical oncology, 2020-12, Vol.17 (12), p.757-770
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ArticlesPeer ReviewedFull Text
RAF inhibitor PLX8394 selectively disrupts BRAF dimers and RAS-independent BRAF-mutant-driven signaling
Author / Creator:Yao, Zhan ; Gao, Yijun ; Su, Wenjing ; Yaeger, Rona ; Tao, Jessica ; Na, Na ; Zhang, Ying ; Zhang, Chao ; Rymar, Andrey ; Tao, Anthony ; Timaul, Neilawattie M. ; Mcgriskin, Rory ; Outmezguine, Nathaniel A. ; Zhao, HuiYong ; Chang, Qing ; Qeriqi, Besnik ; Barbacid, Mariano ; de Stanchina, Elisa ; Hyman, David M ; Bollag, Gideon ; Rosen, Neal
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2019-02, Vol.25 (2), p.284-291
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Retained mismatch repair protein expression occurs in approximately 6% of microsatellite instability-high cancers and is associated with missense mutations in mismatch repair genes
Author / Creator:Hechtman, Jaclyn F. ; Rana, Satshil ; Middha, Sumit ; Stadler, Zsofia K. ; Latham, Alicia ; Benayed, Ryma ; Soslow, Robert ; Ladanyi, Marc ; Yaeger, Rona ; Zehir, Ahmet ; Shia, Jinru
Publisher:New York: Nature Publishing Group US
Journal title:Modern pathology, 2020-05, Vol.33 (5), p.871-879
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Resistance to TRK inhibition mediated by convergent MAPK pathway activation
Author / Creator:Cocco, Emiliano ; Schram, Alison M. ; Kulick, Amanda ; Misale, Sandra ; Won, Helen H. ; Yaeger, Rona ; Razavi, Pedram ; Ptashkin, Ryan ; Hechtman, Jaclyn F. ; Toska, Eneda ; Cownie, James ; Somwar, Romel ; Shifman, Sophie ; Mattar, Marissa ; Selçuklu, S. Duygu ; Samoila, Aliaksandra ; Guzman, Sean ; Tuch, Brian B. ; Ebata, Kevin ; de Stanchina, Elisa ; Nagy, Rebecca J. ; Lanman, Richard B. ; Houck-Loomis, Brian ; Patel, Juber A. ; Berger, Michael F. ; Ladanyi, Marc ; Hyman, David M. ; Drilon, Alexander ; Scaltriti, Maurizio
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2019-09, Vol.25 (9), p.1422-1427
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Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesions
Author / Creator:Brannon, A Rose ; Vakiani, Efsevia ; Sylvester, Brooke E ; Scott, Sasinya N ; McDermott, Gregory ; Shah, Ronak H ; Kania, Krishan ; Viale, Agnes ; Oschwald, Dayna M ; Vacic, Vladimir ; Emde, Anne-Katrin ; Cercek, Andrea ; Yaeger, Rona ; Kemeny, Nancy E ; Saltz, Leonard B ; Shia, Jinru ; D’Angelica, Michael I ; Weiser, Martin R ; Solit, David B ; Berger, Michael F
Publisher:England: BioMed Central Ltd
Journal title:Genome Biology (Online Edition), 2014-08, Vol.15 (8), p.454-454, Article 454
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Immune biomarkers and response to checkpoint inhibition of BRAFV600 and BRAF non-V600 altered lung cancers
Author / Creator:Murciano-Goroff, Yonina R. ; Pak, Terry ; Mondaca, Sebastian ; Flynn, Jessica R. ; Montecalvo, Joseph ; Rekhtman, Natasha ; Halpenny, Darragh ; Plodkowski, Andrew J. ; Wu, Stephanie L. ; Kris, Mark G. ; Paik, Paul K. ; Riely, Gregory J. ; Yu, Helena A. ; Rudin, Charles M. ; Hellmann, Matthew D. ; Land, Josiah D. ; Buie, Larry W. ; Heller, Glenn ; Lito, Piro ; Yaeger, Rona ; Drilon, Alexander ; Liu, Dazhi ; Li, Bob T. ; Offin, Michael
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2022-04, Vol.126 (6), p.889-898
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Functional landscapes of POLE and POLD1 mutations in checkpoint blockade-dependent antitumor immunity
Author / Creator:Ma, Xiaoxiao ; Riaz, Nadeem ; Samstein, Robert M. ; Lee, Mark ; Makarov, Vladimir ; Valero, Cristina ; Chowell, Diego ; Kuo, Fengshen ; Hoen, Douglas ; Fitzgerald, Conall W. R. ; Jiang, Hui ; Alektiar, Jonathan ; Alban, Tyler J. ; Juric, Ivan ; Parthasarathy, Prerana Bangalore ; Zhao, Yu ; Sabio, Erich Y. ; Verma, Richa ; Srivastava, Raghvendra M. ; Vuong, Lynda ; Yang, Wei ; Zhang, Xiao ; Wang, Jingming ; Chu, Lawrence K. ; Wang, Stephen L. ; Kelly, Daniel W. ; Pei, Xin ; Chen, Jiapeng ; Yaeger, Rona ; Zamarin, Dmitriy ; Zehir, Ahmet ; Gönen, Mithat ; Morris, Luc G. T. ; Chan, Timothy A.
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2022-07, Vol.54 (7), p.996-1012
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Integrated clinical and genomic analysis identifies driver events and molecular evolution of colitis-associated cancers
Author / Creator:Chatila, Walid K. ; Walch, Henry ; Hechtman, Jaclyn F. ; Moyer, Sydney M. ; Sgambati, Valeria ; Faleck, David M. ; Srivastava, Amitabh ; Tang, Laura ; Benhamida, Jamal ; Ismailgeci, Dorina ; Campos, Carl ; Wu, Fan ; Chang, Qing ; Vakiani, Efsevia ; de Stanchina, Elisa ; Weiser, Martin R. ; Widmar, Maria ; Yantiss, Rhonda K. ; Shah, Manish A. ; Bass, Adam J. ; Stadler, Zsofia K. ; Katz, Lior H. ; Mellinghoff, Ingo K. ; Sethi, Nilay S. ; Schultz, Nikolaus ; Ganesh, Karuna ; Kelsen, David ; Yaeger, Rona
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-01, Vol.14 (1), p.110-110, Article 110
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Primary Tumor Location and Outcomes After Cytoreductive Surgery and Intraperitoneal Chemotherapy for Peritoneal Metastases of Colorectal Origin
Author / Creator:Adileh, Mohammad ; Yuval, Jonathan B. ; Walch, Henry S. ; Chatila, Walid K. ; Yaeger, Rona ; Garcia-Aguilar, Julio ; Schultz, Nikolaus ; Paty, Philip B. ; Cercek, Andrea ; Nash, Garrett M.
Publisher:Cham: Springer International Publishing
Journal title:Annals of surgical oncology, 2021-02, Vol.28 (2), p.1109-1117
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Alliance for clinical trials in Oncology (Alliance) trial A022101/NRG-GI009: a pragmatic randomized phase III trial evaluating total ablative therapy for patients with limited metastatic colorectal ca...
Author / Creator:Hitchcock, Kathryn E. ; Miller, Eric D. ; Shi, Qian ; Dixon, Jesse G. ; Gholami, Sepideh ; White, Sarah B. ; Wu, Christina ; Goulet, Christopher C. ; George, Manju ; Jee, Kyung-Wook ; Wright, Chadwick L. ; Yaeger, Rona ; Shergill, Ardaman ; Hong, Theodore S. ; George, Thomas J. ; O’Reilly, Eileen M. ; Meyerhardt, Jeffrey A. ; Romesser, Paul B.
Publisher:England: BioMed Central
Journal title:BMC cancer, 2024-02, Vol.24 (1), p.201-9, Article 201
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Rare BRAF mutations in pancreatic neuroendocrine tumors may predict response to RAF and MEK inhibition
Author / Creator:Allen, Amy ; Qin, Alice Can Ran ; Raj, Nitya ; Wang, Jiawan ; Uddin, Sharmeen ; Yao, Zhan ; Tang, Laura ; Meyers, Paul A. ; Taylor, Barry S. ; Berger, Michael F. ; Yaeger, Rona ; Reidy-Lagunes, Diane ; Pratilas, Christine A.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2019-06, Vol.14 (6), p.e0217399
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Type of recurrence is associated with disease-free survival after salvage surgery for locally recurrent rectal cancer
Author / Creator:Jimenez-Rodriguez, Rosa M. ; Yuval, Jonathan B. ; Sauve, Charles-Etienne Gabriel ; Wasserman, Isaac ; Aggarwal, Piyush ; Romesser, Paul B. ; Crane, Christopher H. ; Yaeger, Rona ; Cercek, Andrea ; Guillem, Jose G. ; Weiser, Martin R. ; Wei, Iris H. ; Widmar, Maria ; Nash, Garrett M. ; Pappou, Emmanouil P. ; Garcia-Aguilar, Julio ; Gollub, Marc J. ; Paty, Philip B. ; Smith, J. Joshua
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:International journal of colorectal disease, 2021-12, Vol.36 (12), p.2603-2611
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Yaeger, Rona Denit

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Yaeger, Rona Denit

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Chromothripsis drives the evolution of gene amplification in cancer

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Encorafenib, Binimetinib, and Cetuximab in BRAF V600E–Mutated Colorectal Cancer

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Heat Shock Factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer

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Different hotspot p53 mutants exert distinct phenotypes and predict outcome of colorectal cancer patients

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S1014 Immune Checkpoint Inhibitors for Colorectal Cancer in Patients With Inflammatory Bowel Disease

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Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer

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ctDNA applications and integration in colorectal cancer: an NCI Colon and Rectal–Anal Task Forces whitepaper

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RAF inhibitor PLX8394 selectively disrupts BRAF dimers and RAS-independent BRAF-mutant-driven signaling

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Retained mismatch repair protein expression occurs in approximately 6% of microsatellite instability-high cancers and is associated with missense mutations in mismatch repair genes

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Resistance to TRK inhibition mediated by convergent MAPK pathway activation

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Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesions

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Immune biomarkers and response to checkpoint inhibition of BRAFV600 and BRAF non-V600 altered lung cancers

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Functional landscapes of POLE and POLD1 mutations in checkpoint blockade-dependent antitumor immunity

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Integrated clinical and genomic analysis identifies driver events and molecular evolution of colitis-associated cancers

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Primary Tumor Location and Outcomes After Cytoreductive Surgery and Intraperitoneal Chemotherapy for Peritoneal Metastases of Colorectal Origin

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Alliance for clinical trials in Oncology (Alliance) trial A022101/NRG-GI009: a pragmatic randomized phase III trial evaluating total ablative therapy for patients with limited metastatic colorectal ca...

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Rare BRAF mutations in pancreatic neuroendocrine tumors may predict response to RAF and MEK inhibition

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Type of recurrence is associated with disease-free survival after salvage surgery for locally recurrent rectal cancer

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