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LXR activation potentiates sorafenib sensitivity in HCC by activating microRNA-378a transcription

LXR activation potentiates sorafenib sensitivity in HCC by activating microRNA-378a transcription

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7392029

LXR activation potentiates sorafenib sensitivity in HCC by activating microRNA-378a transcription

About this item

Full title

LXR activation potentiates sorafenib sensitivity in HCC by activating microRNA-378a transcription

Publisher

Australia: Ivyspring International Publisher Pty Ltd

Journal title

Theranostics, 2020-01, Vol.10 (19), p.8834-8850

Language

English

Formats

Publication information

Publisher

Australia: Ivyspring International Publisher Pty Ltd

More information

Scope and Contents

Contents

Sorafenib resistance is a major obstacle to the treatment of advanced hepatocellular carcinoma (HCC). MicroRNAs (miRNAs) are multifunctional regulators of gene expression with profound impact for human disease. Therefore, better understanding of the biological mechanisms of abnormally expressed miRNAs is critical to discovering novel, promising the...

Alternative Titles

Full title

LXR activation potentiates sorafenib sensitivity in HCC by activating microRNA-378a transcription

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7392029

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7392029

Other Identifiers

ISSN

1838-7640

E-ISSN

1838-7640

DOI

10.7150/thno.45158

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