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Muscarinic receptors promote castration-resistant growth of prostate cancer through a FAK–YAP signal...

Muscarinic receptors promote castration-resistant growth of prostate cancer through a FAK–YAP signal...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7428076

Muscarinic receptors promote castration-resistant growth of prostate cancer through a FAK–YAP signaling axis

About this item

Full title

Muscarinic receptors promote castration-resistant growth of prostate cancer through a FAK–YAP signaling axis

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2020-05, Vol.39 (20), p.4014-4027

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Prostate cancer (PCa) innervation contributes to the progression of PCa. However, the precise impact of innervation on PCa cells is still poorly understood. By focusing on muscarinic receptors, which are activated by the nerve-derived neurotransmitter acetylcholine, we show that muscarinic receptors 1 and 3 (m1 and m3) are highly expressed in PCa c...

Alternative Titles

Full title

Muscarinic receptors promote castration-resistant growth of prostate cancer through a FAK–YAP signaling axis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7428076

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7428076

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/s41388-020-1272-x

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