β-catenin S45F mutation results in apoptotic resistance
β-catenin S45F mutation results in apoptotic resistance
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Wnt/β-catenin signaling is one of the key cascades regulating embryogenesis and tissue homeostasis; it has also been intimately associated with carcinogenesis. This pathway is deregulated in several tumors, including colorectal cancer, breast cancer, and desmoid tumors. It has been shown that
CTNNB1
exon 3 mutations are associated with an agg...
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Full title
β-catenin S45F mutation results in apoptotic resistance
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7441052
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7441052
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-020-1382-5
